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Original Article

Nutritional Status and Body Composition in Korean Myopathy Patients

Soo Yun Jang1orcid, Seong-Woong Kang2, Won Ah Choi2, Jang Woo Lee2, Mi Ri Suh2, Song Mi Lee3, Yoo Kyoung Park1orcid
Clinical Nutrition Research 2016;5(1):43-54.
Published online: January 29, 2016

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Corresponding author: Yoo Kyung Park. Address Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea. Tel +82-31-201-3816, Fax +82-31-203-3816, ypark@khu.ac.kr
• Received: December 17, 2015   • Revised: January 15, 2016   • Accepted: January 19, 2016

© 2016 The Korean Society of Clinical Nutrition

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Nutritional Status and Body Composition in Korean Myopathy Patients
Clin Nutr Res. 2016;5(1):43-54.   Published online January 29, 2016
DOI: https://doi.org/10.7762/cnr.2016.5.1.43
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Nutritional Status and Body Composition in Korean Myopathy Patients
Clin Nutr Res. 2016;5(1):43-54.   Published online January 29, 2016
DOI: https://doi.org/10.7762/cnr.2016.5.1.43
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Nutritional Status and Body Composition in Korean Myopathy Patients
Nutritional Status and Body Composition in Korean Myopathy Patients
(n = 12)Total
(n = 73)Energy, kcal1253.9 ± 374.3*1123.9 ± 382.21226.7 ± 388.81090.5 ± 275.01158.0 ± 365.3Carbohydrate, g175.1 ± 48.6157.3 ± 53.7186.1 ± 67.2163.5 ± 38.2165.9 ± 53.1Dietary fiber, g15.1 ± 4.113.5 ± 6.216.9 ± 9.815.5 ± 6.314.6 ± 6.6Total fat, g37.5 ± 23.535.7 ± 17.333.3 ± 12.228.1 ± 12.034.5 ± 17.2 Vegetable fat, g16.5 ± 7.219.5 ± 9.718.9 ± 10.815.6 ± 9.718.3 ± 9.4 Animal fat, g21.1 ± 17.516.2 ± 14.814.4 ± 10.712.5 ± 6.416.2 ± 13.8Cholesterol, mg305.0 ± 278.9236.3 ± 226.9275.9 ± 214.6329.6 ± 210.9269.0 ± 231.0Total Protein, g55.6 ± 17.046.9 ± 19.651.2 ± 20.548.5 ± 13.049.4 ± 18.4 Plant protein, g25.8 ± 7.223.7 ± 10.129.2 ± 14.924.4 ± 7.925.0 ± 10.2 Animal protein, g29.8 ± 16.123.2 ± 13.722.0 ± 11.024.1 ± 8.524.3 ± 13.2Vitamin A, ug RE505.2 ± 312.5668.2 ± 785.1744.2 ± 644.7717.9 ± 528.8658.0 ± 658.0Retinol, ug105.6 ± 93.187.6 ± 85.3110.2 ± 96.3119.2 ± 127.999.1 ± 94.4β-carotene, ug2400.5 ± 1443.43493.1 ± 4722.23804.1 ± 3936.13591.9 ± 3035.53358.4 ± 3918.6Vitamin D, ug4.1 ± 3.03.2 ± 4.34.9 ± 4.73.4 ± 3.53.6 ± 4.0Vitamin E, mg10.9 ± 5.69.8 ± 4.910.6 ± 5.810.0 ± 4.910.1 ± 5.1Vitamin K, ug161.5 ± 129.6206.8 ± 320.1215.6 ± 201.3259.0 ± 260.2207.9 ± 266.1Vitamin C, mg78.3 ± 85.067.0 ± 53.967.5 ± 35.389.2 ± 69.172.5 ± 60.1Thiamin, mg1.0 ± 0.50.8 ± 0.50.8 ± 0.30.8 ± 0.30.9 ± 0.4Riboflavin, mg0.9 ± 0.40.9 ± 0.51.0 ± 0.50.9 ± 0.50.9 ± 0.5Niacin, mg12.4 ± 5.010.3 ± 5.58.6 ± 4.69.7 ± 3.510.3 ± 5.0Vitamin B6, ug1.1 ± 0.31.0 ± 0.41.1 ± 0.61.1 ± 0.31.0 ± 0.4Folate, ug458.1 ± 169.2394.1 ± 262.6449.8 ± 242.2460.7 ± 249.8424.3 ± 240.5Vitamin B12, ug5.9 ± 4.57.1 ± 5.28.9 ± 5.912.4 ± 8.08.0 ± 6.0Pantothennic acid, mg4.1 ± 1.23.5 ± 1.24.3 ± 1.63.3 ± 0.83.7 ± 1.3Biotin, ug16.8 ± 13.614.6 ± 12.816.2 ± 12.916.0 ± 11.415.4 ± 12.5Total Calcium, mg398.6 ± 190.4378.7 ± 147.1528.9 ± 321.7426.8 ± 157.7412.6 ± 194.8 Animal Calcium, mg202.6 ± 87.0191.4 ± 112.6248.8 ± 156.9195.6 ± 82.4202.8 ± 111.9 Vegetable Calcium, mg196.0 ± 165.4187.3 ± 108.9280.1 ± 352.8231.2 ± 129.5209.8 ± 177.9Phosphorus, mg862.4 ± 277.8721.8 ± 251.7860.7 ± 325.8788.5 ± 179.3778.6 ± 262.0Sodium, mg3174.3 ± 966.12730.7 ± 1545.72727.1 ± 1897.83514.3 ± 1356.72929.9 ± 1492.2Chloride, mg356.0 ± 317.1445.8 ± 962.3373.4 ± 411.9209.2 ± 116.2382.4 ± 720.6Potassium, mg1860.9 ± 552.21732.2 ± 727.72129.0 ± 1020.61867.0 ± 561.21836.7 ± 728.2Magnesium, mg57.4 ± 35.449.6 ± 31.955.0 ± 38.147.3 ± 22.651.5 ± 31.9Total iron, mg9.6 ± 2.411.7 ± 9.210.9 ± 5.510.2 ± 3.210.9 ± 7.1 Animal iron, mg7.1 ± 1.98.8 ± 8.68.8 ± 4.87.5 ± 2.78.3 ± 6.5 Vegetable iron, mg2.5 ± 1.62.8 ± 2.62.1 ± 1.12.7 ± 1.52.6 ± 2.1Zinc, mg7.6 ± 2.56.4 ± 2.56.9 ± 2.26.8 ± 1.86.8 ± 2.3Copper, mg0.8 ± 0.30.8 ± 0.40.9 ± 0.40.8 ± 0.20.8 ± 0.3Fluorine, ug5.9 ± 9.29.0 ± 24.63.6 ± 7.84.1 ± 4.66.9 ± 18.4Manganese, mg2.8 ± 0.72.3 ± 1.22.9 ± 1.32.9 ± 0.72.6 ± 1.1Iodine, ug92.3 ± 68.0325.6 ± 792.2179.1 ± 230.0557.0 ± 745.7296.4 ± 652.3Selenium, ug86.0 ± 36.170.9 ± 37.969.8 ± 28.871.8 ± 26.073.6 ± 34.6 (n = 12)p for trendPhA, °2.62 ± 0.87*2.45 ± 0.752.84 ± 0.992.30 ± 0.700.671Intracellular water (ICW), L9.9 ± 3.110.5 ± 2.811.0 ± 3.313.5 ± 2.90.009‡Extracellular water (ECW), L7.4 ± 2.27.4 ± 1.98.0 ± 2.59.7 ± 2.00.014†Total body water (TBW), L17.3 ± 5.317.9 ± 4.419.0 ± 5.923.1 ± 4.80.006‡ECW/TBW0.429 ± 0.0140.415 ± 0.0460.419 ± 0.0100.418 ± 0.0090.026%TBW/FFM, %71.4 ± 2.371.9 ± 1.972.9 ± 2.073.6 ± 0.80.000§Protein, kg4.3 ± 1.44.5 ± 1.24.8 ± 1.55.8 ± 1.30.009‡Mineral, kg2.5 ± 0.62.4 ± 0.52.2 ± 0.62.4 ± 0.40.721Soft lean mass (SLM), kg21.8 ± 6.722.7 ± 5.724.2 ± 7.429.3 ± 6.20.010†Fat free mass (FFM), kg24.1 ± 6.824.8 ± 6.026.0 ± 7.631.4 ± 6.30.010†Fat mass (FM), kg12.5 ± 13.713.5 ± 11.420.6 ± 14.528.3 ± 13.80.001‡%Body fat (%BF), %29.0 ± 18.930.4 ± 17.839.5 ± 13.344.3 ± 14.30.014†Skeletal muscle mass (SMM), kg10.9 ± 4.111.6 ± 3.612.4 ± 4.415.6 ± 3.80.009‡Body cell mass (BCM), kg14.2 ± 4.415.0 ± 3.915.8 ± 4.819.3 ± 4.20.009‡Bone mineral content (BMC), kg2.2 ± 0.62.1 ± 0.51.9 ± 0.52.1 ± 0.30.446
Table 1 General characteristics of subjects

BMI: body mass index, PIBW: percentage of ideal body weight.

*Mean ± SD; Significance as determined by Jonckheere-Terpstra test, p for trend less than †p < 0.05; ‡p < 0.01.

Table 2 Pearson correlation coefficient of general characteristics, blood index and bioelectrical impedance analysis (BIA)

PhA: phase angle, between 3° and 15° in the majority of human beings.

Significance as determined by the Pearson correlation method, p for trend less than *p < 0.05; †p < 0.01.

Table 3 Pearson correlation coefficient of nutrient analysis, blood index, and quality of life (QOL)

Significance as determined by the Pearson correlation method, p for trend less than *p < 0.05; †p < 0.01.

Table 4 General chemistry in subjects

BUN: blood urea nitrogen, ALP: alkaline phosphatase, AST: aspartate aminotransferase, ALT: alanine aminotransferase, LD: lactate dehydrogenase, CK: creatine kinase, eGFR: estimated glomerular filtration rate, BNP: B type natriuretic peptide.

*Mean ± SD; Significance as determined by Jonckheere-Terpstra test, p for trend less than †p < 0.05; ‡p < 0.01.

Table 5 Complete blood count in subjects

WBC: white blood cell, RBC: red blood cell, MCV: mean corpuscular volume, MCH: mean corpuscular hemoglobin, MCHC: mean corpuscular hemoglobin concentration, RDW: red cell distribution width, PDW: platelet distribution width, MPV: mean plasma volume, PLT: platelet, ESR: erythrocyte sedimentation rate.

*Mean ± SD; Significance as determined by the Jonckheere-Terpstra test, p for trend less than †p < 0.001.

Table 6 WHOQOL-BREF scores of subjects

WHOQOL-BREF: world health organization quality of life-BREF.

*Mean ± SD; Significance as determined by the Jonckheere-Terpstra test, p for trend less than †p < 0.05; ‡p < 0.01.

Table 7 Nutritional intakes of subjects

*Mean ± SD.

Table 8 Bioelectrical impedance analysis (BIA) data of subjects

PhA: phase angle, between 3° and 15° in the majority of human beings, ECW/TBW: extracellular water/total body water, TBW/FFM: total body water/fat free mass.

*Mean ± SD; Significance as determined by the Jonckheere-Terpstra test, p for trend less than †p < 0.05; ‡p < 0.01; §p < 0.001.

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