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"Nutrition therapy"

Case Reports

[English]
Clinical Impact of Nutritional Intervention on Pressure Injury Healing in a Paraplegic Patient: A Case Report
Young ran Kim, Mi young Jang, Jun ho Park
Clin Nutr Res 2025;14(4):241-246.   Published online October 31, 2025
DOI: https://doi.org/10.7762/cnr.2025.14.4.241

Pressure injuries are common complications in patients with limited mobility, particularly those who are bedridden. These wounds not only cause pain and reduce quality of life but also lead to prolonged hospitalization, increased risk of infection, and higher healthcare costs. Among the various contributing factors, malnutrition plays a crucial role by impairing collagen synthesis, weakening immune function, and delaying tissue repair. Adequate nutritional support—particularly sufficient protein and energy intake—is therefore an essential component of comprehensive pressure injury management. We present the case of a paraplegic patient who developed a vulvar pressure injury. A structured, stepwise nutritional intervention was implemented, including adjustment of meal composition based on appetite, supplementation with high-protein oral nutritional supplements, vitamins and minerals, and the use of probiotics to manage diarrhea. As a result, the patient’s daily protein intake increased from less than 10 g to 80–90 g, accompanied by progressive wound improvement. Serial clinical assessments showed reduced slough, increased granulation tissue formation, and epithelialization. This case highlights the vital role of individualized nutritional management within a multidisciplinary approach to pressure injury care. Stepwise nutritional intervention, tailored to the patient’s tolerance and clinical status, contributed significantly to wound healing. Nutritional optimization should be considered an integral component of effective pressure injury treatment strategies.

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[English]
Nutrition Intervention for Older Patients Based on Comprehensive Geriatric Assessment: A Case Report
Dasom Park, Ah-Reum Shin, Youngmi Park
Clin Nutr Res 2025;14(2):91-99.   Published online April 28, 2025
DOI: https://doi.org/10.7762/cnr.2025.14.2.91

Malnutrition is prevalent among older patients, leading to increased morbidity, prolonged hospitalization, and diminished quality of life. The Comprehensive Geriatric Assessment (CGA) facilitates the evaluation of multifaceted health issues, enabling individualized nutritional interventions. This case report describes nutritional management guided by CGA in a 75-year-old female hospitalized for severe hypernatremia with significant malnutrition and high-risk for refeeding syndrome. Upon admission, CGA identified multiple comorbidities, cognitive impairment, and complete dependence on caregivers for daily activities. Due to persistent refusal of oral intake, enteral nutrition (EN) was cautiously initiated at 25% of the target energy requirement, with close monitoring of electrolyte levels. Despite an initial decrease in phosphorus levels suggestive of refeeding syndrome, gradual advancement of nutritional support successfully stabilized her clinical condition. Following discharge, structured caregiver education was provided to support EN at home; however, suboptimal intake persisted due to gastrointestinal intolerance, resulting in weight loss. Post-discharge follow-ups identified feeding rate-related symptoms, necessitating formula adjustments and caregiver re-education. This case emphasizes the critical role of CGA in early malnutrition detection, individualized nutritional intervention, prevention of refeeding syndrome, and the importance of continuous post-discharge monitoring and caregiver education. Although the findings are limited by the single-case design, proactive CGA-based nutritional interventions remain crucial for optimizing clinical outcomes in older patients hospitalized due to acute medical problems. Further research involving larger samples and prolonged follow-up periods is required to validate the long-term benefits of CGA-based nutritional intervention.

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Special Report

[English]
Korean Food Exchange Lists for Diabetes Meal Planning: Revised 2023
Jae Won Cho, Dal Lae Ju, YeonHee Lee, Bo Kyung Min, Meera Kweon, Eun Mi Kim, SuJin Song, Jae Eun Shim, Oh Yoen Kim, Suk Chon, Jeong Hyun Lim
Clin Nutr Res 2024;13(4):227-237.   Published online October 29, 2024
DOI: https://doi.org/10.7762/cnr.2024.13.4.227

A food exchange list is a tool developed to help diabetic patients control their energy intake and plan balanced meals. Korean food exchange lists were first developed in 1988, revised in 1995, and updated again in 2010. With rapidly changing dietary habits and increasing demand for diverse food cultures, the Korean Diabetes Association in cooperation with 4 related organizations established a Task Force Team (TFT) to revise food exchange lists in March 2022. Starting with a workshop, TFT held 11 official revision meetings, culminating in a public hearing in May 2023. The final revised version of Korean food exchange lists was published in December 2023. Key outcomes of the revision are summarized as follows: 1. Based on the National Standard Food Composition Table 10.0 database, the existing classification system and nutrient standards for each food group remain unchanged this time. 2. Based on a survey conducted among diabetes educators, the number of items on the food exchange lists has increased from 339 in 2010 to 435 this time. 3. Considering patients’ usual eating habits, meal planning examples were developed distributing food group exchange units by energy level based on 3 types of proportions of carbohydrate energy (40%–45%, 50%–55%, 60%–65%). 4. Due to limitations in real-time updates for rapidly changing information, detailed guidance on how to access and interpret the data is provided. These revisions will help people with diabetes manage their blood sugar levels and facilitate the implementation of healthy meal planning in various other conditions, including obesity.

Citations

Citations to this article as recorded by  
  • Development of Nutritional Counseling Materials for ASD Children: Focusing on the Food Exchange List
    Seunghyun Won, Youjeong Kim, Jiye Park, Su-In Yoon, Jin Ah Cho
    Clinical Nutrition Research.2025; 14(2): 127.     CrossRef
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Case Reports

[English]
Nutrition Intervention in a Gastric Cancer Patient With Gastrectomy for 12 Months: A Case Report
So Young Youn, Bo Eun Kim, Eun Mee Kim
Clin Nutr Res 2023;12(1):1-6.   Published online January 26, 2023
DOI: https://doi.org/10.7762/cnr.2023.12.1.1

Gastrectomy is the most effective method of treating gastric cancer, but it is commonly associated with weight loss, nutritional deficiencies, and the increased risk of malnutrition due to post-surgery complications, including gastric stasis, dumping syndrome, malabsorption, and maldigestion. Malnutrition is a risk factor for postoperative complications and poor prognosis. To prevent it and guarantee a quick recovery after surgery, continuous and individualized nutrition intervention should be performed both before surgery and postoperatively. The Department of Dietetics at Samsung Medical Center (SMC) performed nutritional status assessment before gastrectomy, initial nutritional assessment within 24 hours of admission, description of therapeutic diet after surgery, nutrition counselling before discharge, and nutritional status assessment and individual nutrition counselling after 1, 3, 6, and 12 months from surgery. This is a case report of a patient who underwent gastrectomy as well as intensive nutrition intervention in SMC.

Citations

Citations to this article as recorded by  
  • A mediation analysis of family members’ knowledge, attitudes, and practices in nutritional and dietary management for gastric cancer patients
    Cailian Liu, Min Wei, Lijuan Song
    Frontiers in Medicine.2026;[Epub]     CrossRef
  • The effect of individual nutrition counseling on the life quality and weight in patients with gastric cancer following total gastrectomy
    Nasrin Keshtkar, Farzad Shidfar, Seyed Ruhollah Miri, Fatemeh Sadat Hosseini-Baharanchi, Rafat Bagherzadeh, Seyed Mojtaba Ghoreishy
    Scientific Reports.2025;[Epub]     CrossRef
  • Effectiveness of the CANCER-AIMS intervention on nutritional status and symptom management in patients with gastric cancer following gastrectomy: A randomized controlled trial
    Liping Ren, Yanan Fu, Zhonghong Wang, Chunqing Ma, Sukhee Ahn, Qinghui Meng
    International Journal of Nursing Studies.2024; 159: 104873.     CrossRef
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[English]
Nutritional Intervention for a Korean Adolescent with Atopic Dermatitis: a Case Report
Sunghee Kim, Sung-Im Lee, Shin-Sook Kang
Clin Nutr Res 2021;10(4):364-370.   Published online October 28, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.4.364

Atopic dermatitis (AD) is a common inflammatory skin disease in children worldwide but can affect individuals of all ages. Patients and parents of pediatric patients tend to restrict too much food because they think this aggravates or causes AD. However, there is a risk of nutrient deficiency owing to a lack of balanced diet. Herein, nutritional counseling was conducted to improve the eating habits of a patient with AD, promote nutritionally balanced meals, and consequently observe changes in the severity of AD. This report discusses the case of a 15-year-old male patient with AD who did not receive nutritional counseling previously but regularly ate breakfast and consumed fruits, beans, vegetables, and milk more frequently after counseling. His vegetable consumption increased from less than one plate a day before counseling to more than eight plates a day after counseling. This change was reflected in the nutritional quotient for adolescents (NQ-A) score. After consultation, eating habits improved, as indicated by a 1.2-, 2.4-, and 1.5-fold increase in NQ-A, diversity category, and balance category scores, respectively. The intake of protein, dietary fiber, vitamin A, vitamin D, vitamin K, vitamin C, niacin, calcium, potassium, magnesium, and water was inadequate before consultation and improved after consultation. The eating habits and severity of AD also improved after nutritional counseling. However, this result was not tested in a tightly controlled environment. It was difficult to conclude that only the eating habits affected the severity. Therefore, further research is needed.

Citations

Citations to this article as recorded by  
  • The Western Diet and Atopic Dermatitis: The Potential Role of Nutrients, Contaminants, and Additives in Dysbiosis and Epithelial Barrier Dysfunction
    Chiara Maria Teresa Boggio, Federica Veronese, Marta Armari, Elisa Zavattaro, Elia Esposto, Paola Savoia, Barbara Azzimonti
    Antioxidants.2025; 14(4): 386.     CrossRef
  • Naturopathic approach towards pediatric atopic dermatitis: A case report
    MR Monicasun, P. Naresh Kumar, Ragavendrasamy Balakrishnan, Tharima Kaliyanthil Leela, Dhilip V. Ravindran
    Journal of Ayurveda Case Reports.2024; 7(2): 97.     CrossRef
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[English]
Nutritional Management in a Patient with Citrullinemia Type 1
Hyejin Kang, Mihyang Kim, Ji Hyun Lee
Clin Nutr Res 2021;10(3):268-277.   Published online July 20, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.3.268

For patients with citrullinemia type 1, nutritional management is essential to prevent the occurrence of complications associated with hyperammonemia. This report describes a patient who had been receiving nutrition intervention for more than 3 years. A newborn diagnosed with hyperammonemia due to citrullinemia visited Ajou University Hospital and was referred to the nutrition team. After receiving acute treatment, the infant was regularly fed with specialized formula. A protein-restricted diet is recommended for maintaining normal development and achieving long-term survival. Through continuous provision of nutritional intervention, the child showed normal growth and development, and the energy-protein supply was maintained appropriately. This case clearly shows the importance of medical nutrition therapy for patients with citrullinemia.

Citations

Citations to this article as recorded by  
  • Beginning of a new era of synthetic messenger RNA therapeutics: Comprehensive insights on mRNA drug design, development and applications
    Saumya Nishanga Heendeniya, Suxiang Chen, Saadia Bhatti, Qurat Ul Ain Zahra, Kamal Rahimizadeh, Bal Hari Poudel, Stephen D. Wilton, Rakesh N. Veedu
    Experimental Biology and Medicine.2025;[Epub]     CrossRef
  • Visualization of argininosuccinate synthetase by in silico analysis: novel insights into citrullinemia type I disorders
    Xia Gu, Wenhui Mo, Guiying Zhuang, Congcong Shi, Tao Wei, Jinze Zhang, Chiaowen Tu, Yao Cai, Biwen Liao, Hu Hao
    Frontiers in Molecular Biosciences.2024;[Epub]     CrossRef
  • Prenatal diagnosis of citrullinemia type 1; seven families with c.1168G>A mutation of Argininosuccinate synthetase 1 gene in Southwest Iran: A case series
    Maryam Hassanlou, Maryam Abiri, Sirous Zeinali
    International Journal of Reproductive BioMedicine (IJRM).2023; 20(12): 1047.     CrossRef
  • Case report: Diagnosis of ADCY5-related dyskinesia explaining the entire phenotype in a patient with atypical citrullinemia type I
    Audrey Pontrucher, Magalie Barth, Alban Ziegler, Juan Manuel Chao de la Barca, Delphine Mirebeau-Prunier, Pascal Reynier, Chadi Homedan
    Frontiers in Neurology.2023;[Epub]     CrossRef
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[English]
Nutrition Intervention Process for Heart Failure Patients according to Their Nutritional Problems
Hosun Lee, Suk Yong Jeong, Hae Ryeon Choi, Seok-Min Kang
Clin Nutr Res 2021;10(2):172-180.   Published online April 23, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.2.172

Patients with heart failure (HF) need nutritional management such as sodium restriction and healthy eating habits to relieve symptoms and to manage chronic disease. This case study examined 3 patients who had different nutritional problems and responded positively to the nutrition management program. Patient 1 and 2 had high levels of energy intake and were obese. Patient 1 had a habit of irregular binge eating and frequently consumed sweetened snacks and fast foods. He was advised to eat regular 3 meals per day with balanced food choices. He decreased his energy consumption to the recommenced intake and his body mass index had dropped to 22.9 kg/m2 by his second follow-up visit. Patients 2 ate 3 meals regularly but ate a large amount of food. Although he decreased his energy intake to 97% of the recommended intake, he should be advised to increase his protein intake at the 1st follow-up session because he decreased his protein intake less than 90% of the recommended amount. Patient 3 reduced food intake by half due to dyspnea caused by HF before hospitalization, but symptoms improved after discharge and his energy as well as sodium intake increased. In the second follow-up, his nutritional diagnosis was excessive sodium intake and nutritional intervention was performed to reduce sodium intake. This study showed that additional nutritional problems might arise throughout the nutritional intervention process. Therefore, follow-up nutritional counseling should be held to evaluate the compliance with the nutrition management guidelines and to decide whether additional nutrition problems are suggested.

Citations

Citations to this article as recorded by  
  • The heart–brain axis: neurocognitive frailty in heart failure
    Olayiwola Bolaji, Yasemin Bahar, Sameer Lohana, Abdul Rasheed Bahar, Ibiyo Lawrence, Sula Mazimba
    Journal of Neurology.2025;[Epub]     CrossRef
  • The Nutritional Status of Patients with Heart Failure and Its Impact on Patient’ Outcomes—The Center’s Own Experience
    Natalia Świątoniowska-Lonc, Marek Aureliusz Mak, Filip Klausa, Krzysztof Ściborski, Waldemar Banasiak, Adrian Doroszko
    Nutrients.2025; 17(5): 761.     CrossRef
  • Prognostic value of nutritional screening tools in hospitalized patients with decompensated heart failure: A systematic review and meta-analysis
    Amanda Farias Osório, Édina Caroline Ternus Ribeiro, Suena Medeiros Parahiba, Gabriele Carra Forte, Nadine Oliveira Clausell, Gabriela Corrêa Souza
    Nutrition Research.2023; 120: 1.     CrossRef
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[English]
A Case Study on the Customized Nutrition Intervention for a Patient with Primary Gastrointestinal Non-Hodgkin Lymphoma Underlying Chronic Kidney Disease
Young-Hwa Song, Han-Na Kwon, Jeong-Im Hong, Juyeon Park, Ji-Yeon Kim, Hye-Jin Kim
Clin Nutr Res 2020;9(4):332-342.   Published online October 29, 2020
DOI: https://doi.org/10.7762/cnr.2020.9.4.332

Non-Hodgkin lymphoma comprises 2.1% of the total number of cancers in South Korea. Among those, diffuse large B cell lymphoma (DLBCL) comprises the largest percentage. Nutrition interventions have been highlighted because nutritional status in non-Hodgkin's lymphoma patients has a significant impact on treatment and prognosis, but relevant studies are inadequate. Therefore, the aim of this study was to share the case of a nutrition intervention for a patient with primary gastrointestinal non-Hodgkin lymphoma underlying chronic kidney disease who was comorbid with tumor lysis syndrome, which was a complication of a specific chemotherapy. The subject is a 76-year-old patient who was diagnosed with DLBCL. He had abdominal pain, constipation, and anorexia. After chemotherapy, he experienced the tumor lysis syndrome. The patient's condition was continuously monitored, and various nutrition interventions, such as nutrition counseling and education, provision of therapeutic diet, oral nutritional supplement, change of meal plans, and parenteral nutrition support were attempted. As a result of the nutrition intervention, oral intake was increased from 27% of the energy requirement to 70% and from 23% of the protein requirement to 77%. Despite the various nutrition interventions during the hospitalization, there were no improvements in weight and nutrition-related biochemical parameters or malnutrition. However, it was meaningful in that the patient was managed to prevent worsening and the planned third chemotherapy could be performed. These results can be used as the basis for establishing guidelines for nutritional interventions customized to patients under the same conditions.

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[English]
Nutritional Management of a Patient with a High-Output Stoma after Extensive Small Bowel Resection to Treat Crohn's Disease
Yun Jung Lee, MeeRa Kweon, Misun Park
Clin Nutr Res 2019;8(3):247-253.   Published online July 29, 2019
DOI: https://doi.org/10.7762/cnr.2019.8.3.247

For patients with short bowel syndrome who undergo ileostomy, nutritional management is essential to prevent complications associated with a high-output stoma (HOS). We report a practical example of ostomic, medical nutrition therapy provided by an intensive nutritional support team (NST). A 42-year-old male with a history of Crohn's disease visited Seoul National University Hospital for treatment of mechanical ileus. He underwent loop ileostomy after extensive small bowel resection. As his remaining small bowel was only 160 cm in length, the stomal output was about 3,000 mL/day and his body weight fell from 52.4 to 40.3 kg. Given his clinical condition, continuous tube feeding for 24 h was used to promote adaptation of the remnant bowel. Thereafter, an oral diet was initiated and multiple, nutritional educational sessions were offered by dietitians. Constant infusion therapy was prescribed and included in the discharge plan. Two months after discharge, his body weight had increased to 46.6 kg and his hydration status was appropriately maintained. This case suggests that the critical features of medical nutritional therapy for ostomy management are frequent assessments of fluid balance, weight history, and laboratory data and after nutritional interventions.

Citations

Citations to this article as recorded by  
  • CYP24A1 in Small Intestinal Vitamin D Metabolism and Clinical Implications
    Agnieszka Nowacka, Maciej Śniegocki, Dominika Bożiłow, Ewa A. Ziółkowska
    Nutrients.2025; 17(21): 3348.     CrossRef
  • Construction and application of home dietary management program for postoperative patients with preventive ileostomy for rectal cancer
    Jianhua Zhu, Yuanjuan Shen, Juyun Li, Sainan Wang, Wenjuan Shang, Min Sun
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Evaluation of pediatric patients for intestinal transplantation in the modern era
    Nathan S. Bryan, Shannon C. Russell, Oguz Ozler, Fumitaka Sugiguchi, Nada A. Yazigi, Khalid M. Khan, Udeme D. Ekong, Bernadette E. Vitola, Juan‐Francisco Guerra, Alexander Kroemer, Thomas M. Fishbein, Cal S. Matsumoto, Shahira S. Ghobrial, Stuart S. Kaufm
    Journal of Pediatric Gastroenterology and Nutrition.2024; 79(2): 278.     CrossRef
  • Exclusive enteral nutrition combined with continuous succus entericus reinfusion for high-output stoma in patients with Crohn’s disease: a case report
    Na Diao, Wenyou Zheng, Huiping Chen, Jian Tang
    Gastroenterology Report.2023;[Epub]     CrossRef
  • Management of gastrointestinal failure in the adult critical care setting
    Mette M. Berger, Claire-Anne Hurni
    Current Opinion in Critical Care.2022; 28(2): 190.     CrossRef
  • Nutritional and Educational Intervention to Recover a Healthy Eating Pattern Reducing Clinical Ileostomy-Related Complications
    Antonio Fernández-Gálvez, Sebastián Rivera, María del Carmen Durán Ventura, Rubén Morilla Romero de la Osa
    Nutrients.2022; 14(16): 3431.     CrossRef
  • The complexities of approaching nutrition in inflammatory bowel disease: current recommendations and future directions
    Lindsey A Russell, Maria Teresa Balart, Pablo Serrano, David Armstrong, Maria Ines Pinto-Sanchez
    Nutrition Reviews.2022; 80(2): 215.     CrossRef
  • Evaluation of interventions in people with digestive stoma through the Nursing Interventions Classification
    Concepción Capilla‐Díaz, Noelia Moya‐Muñoz, José Manuel Matas‐Terrón, María Ángeles Pérez‐Morente, María Adelaida Álvarez‐Serrano, Rafael Montoya‐Juárez, César Hueso‐Montoro
    International Journal of Nursing Knowledge.2022; 33(1): 40.     CrossRef
  • Lower ileostomy output among patients with postoperative colorectal cancer after being supplemented with partially hydrolyzed guar gum: Outcome of a pilot study
    Chiou Yi Ho, Hazreen Abdul Majid, Norshariza Jamhuri, Atiki Falparado Ahmad, Tharmasilen A/L Selvarajoo
    Nutrition.2022; 103-104: 111758.     CrossRef
  • A holistic view of the stoma care pathway in Italy: a nationwide learning survey
    Elena Toma, Filippo La Torre, Filippo Barone, Marcello Rovere, Maria Sole Ercolani, Paola Pocek, Lucia Filomeno, Giuseppe La Torre
    Gastrointestinal Nursing.2022; 20(Sup4): S24.     CrossRef
  • Pre- and Post-Operative Nutrition Assessment in Patients with Colon Cancer Undergoing Ileostomy
    Georgios Vasilopoulos, Panagiota Makrigianni, Maria Polikandrioti, Ilias Tsiampouris, Dimitrios Karayiannis, Nikoletta Margari, Lamprini Avramopoulou, Georgia Toulia, Georgia Fasoi
    International Journal of Environmental Research and Public Health.2020; 17(17): 6124.     CrossRef
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[English]
In-depth Medical Nutrition Therapy for a Woman with Diabetes: From Pregnancy to Delivery
Miyoung Jang, Dal Lae Ju, MeeRa Kweon, Misun Park
Clin Nutr Res 2016;5(4):305-309.   Published online October 31, 2016
DOI: https://doi.org/10.7762/cnr.2016.5.4.305

Diabetes in pregnancy is associated with higher rates of miscarriage, pre-eclampsia, preterm labor, and fetal malformation. To prevent these obstetric and perinatal complications, women with diabetes have to control levels of blood sugar, both prior to and during pregnancy. Thus, individualized medical nutrition therapy for each stage of pregnancy is essential. We provided in-depth medical nutrition therapy to a 38-year-old pregnant woman with diabetes at all stages of pregnancy up to delivery. She underwent radiation therapy after surgery for breast cancer and was diagnosed with diabetes. At the time of diagnosis, her glycated hemoglobin level was 8.3% and she was planning her pregnancy. She started taking an oral hypoglycemic agent and received education regarding the management of diabetes and preconception care. She became pregnant while maintaining a glycated hemoglobin level of less than 6%. We provided education program for diabetes management during the pregnancy, together with insulin therapy. She experienced weight loss and ketones were detected; furthermore, she was taking in less than the recommended amount of foods for the regulation of blood sugar levels. By giving emotional support, we continued the counseling and achieved not only glycemic control but also instilled an appreciation of the importance of appropriate weight gain and coping with difficulties. Through careful diabetes management, the woman had a successful outcome for her pregnancy, other than entering preterm labor at 34 weeks. This study implicated that the important things in medical nutrition therapy for pregnant women with diabetes are frequent follow-up care and emotional approach through the pregnancy process.

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[English]
Six-month Outcomes of Mobile Phone Application-based Self-management in a Patient with Type 2 Diabetes
Mi Kyeong Hong, Young Yun Cho, Mi Yong Rha, Jae Hyeon Kim, Moon-Kyu Lee
Clin Nutr Res 2015;4(3):201-207.   Published online July 31, 2015
DOI: https://doi.org/10.7762/cnr.2015.4.3.201

We report the case in order to examine the effect of a mobile application program ("Diabetes & Nutrition") developed in 2011-2012 for self-management in patients with type 2 diabetes and to recommend important considerations when the mobile application program is developed. A 46-year-old man was newly diagnosed with type 2 diabetes in 2013 and had no complications. The height of the patient was 168 cm and the body weight was 75.6 kg. Nutrition education was conducted according to a medical prescription, and follow-up nutrition education was conducted after 3 and 6 months. After nutrition education, the patient was engaged in self-management using "Diabetes & Nutrition" program during 3 months. At 3 months, the body weight had decreased by 4.4 kg (from 75.6 to 71.2 kg), waist circumference by 5 cm (from 88 to 83 cm) and HbA1c level from 7.9% to 6.1%. Also at 3 months, the medication was reduced from from the dose of 850 mg to the dose of 500 mg metformin per twice a day. Since then, the patient did not continue to use the "Diabetes & Nutrition" because the level of blood glucose had stabilized, and the patient felt inconvenient and annoying to use the program. At 6 months, no significant change in the body weight and body composition was observed in comparison with those at 3 months. The present case demonstrates that the early use of "Diabetes & Nutrition" could be helpful for self-management of glycemic control in patients with type 2 diabetes. Developing self-management mobile application programs in the future will require strategies of how to promote continuous use of application program and self-management of type 2 diabetes.

Citations

Citations to this article as recorded by  
  • Behavior Change Effectiveness Using Nutrition Apps in People With Chronic Diseases: Scoping Review
    Emily Salas-Groves, Shannon Galyean, Michelle Alcorn, Allison Childress
    JMIR mHealth and uHealth.2023; 11: e41235.     CrossRef
  • Identifying features of a mobile-based application for self-care of people living with T2DM
    Esmaeil Mehraeen, Tayebeh Noori, Zahra Nazeri, Mohammad Heydari, Adele Mehranfar, Hamed Rezakhani Moghaddam, Vahideh Aghamohammadi
    Diabetes Research and Clinical Practice.2021; 171: 108544.     CrossRef
  • Prototypes of User Interfaces for Mobile Applications for Patients with Diabetes
    Jan Pavlas, Ondrej Krejcar, Petra Maresova, Ali Selamat
    Computers.2018; 8(1): 1.     CrossRef
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[English]
Nutrition Therapy for Mitochondrial Neurogastrointestinal Encephalopathy with Homozygous Mutation of the TYMP Gene
Jing Wang, Wei Chen, Fang Wang, Dong Wu, Jiaming Qian, Junren Kang, Hailong Li, Enling Ma
Clin Nutr Res 2015;4(2):132-136.   Published online January 16, 2015
DOI: https://doi.org/10.7762/cnr.2015.4.2.132

Mitochondrial neurogastrointestinal encephalopathy (MNGIE) is characterized by significant gastrointestinal dysmotility. Early and long-term nutritional therapy is highly recommended. We report a case of MNGIE in a patient who was undergoing long-term nutrition therapy. The patient was diagnosed with a serious symptom of fatty liver and hyperlipidemia complications, along with homozygous mutation of the thymidine phosphorylase (TYMP) gene (c.217G > A). To our knowledge, this is the first report of such a case. Herein, we describe preventive measures for the aforementioned complications and mitochondrial disease-specific nutritional therapy.

Citations

Citations to this article as recorded by  
  • New Insights into Folate–Vitamin B12 Interactions
    Luisa F. Castillo, Caitlyn M. Pelletier, Katarina E. Heyden, Martha S. Field
    Annual Review of Nutrition .2025; 45(1): 23.     CrossRef
  • A CEBPB/TYMP/GDF15 signaling axis mediates tumor growth and cisplatin resistance in bladder cancer
    Shuo Tian, Chuang Wang, Xupeng Zhao, Yundong Xuan, Wenjie Wei, Yuhao Dong, Wen Tao, Chi Zhang, Tianwei Cai, Chunyu Liu, Yan Huang, Xu Zhang
    Translational Oncology.2025; 61: 102537.     CrossRef
  • Thymidine phosphorylase associates with DNA damage repair to facilitate stemness maintenance, chemoresistance, and immunosuppression in pan-cancer
    Pan Liao, Zhaoli Han, Bo Yan, Fanglian Chen, Ping Lei
    International Journal of Biological Macromolecules.2025; 319: 145707.     CrossRef
  • Nutritional management in MNGIE disease: A case report
    Tuğçe Kartal, Sema Uzunoğlu, İrem Kaplan, Fatma Derya Bulut, Deniz Kor, Neslihan Önenli Mungan
    Clinical Science of Nutrition.2025; 7(1): 63.     CrossRef
  • Untargeted Plasma Metabolomics Extends the Biomarker Profile of Mitochondrial Neurogastrointestinal Encephalomyopathy
    Bridget E. Bax, Sema Kalkan Uçar
    International Journal of Molecular Sciences.2025; 26(18): 9107.     CrossRef
  • Thymidine phosphorylase participates in platelet activation and promotes inflammation in rheumatoid arthritis
    Bo Cai, Zelin He, Dandan Liu, Yuping Zhang, Zikang Yin, Weijia Bao, Qiaoyi Le, Ju Shao, Hongyan Du, Ligang Jie
    Toxicology and Applied Pharmacology.2025; 495: 117217.     CrossRef
  • Expansion of the Phenotypic Spectrum of MNGIE: Lipodystrophy and Metabolic Alterations Associated with a p.Arg393_Val400dup TYMP Variant
    Donatella Gilio, Caterina Pelosini, Silvia Magno, Jacopo Maria Venanzi, Marta Daniotti, Melania Paoli, Lavinia Palladino, Maria Rita Sessa, Franco Ricci, Elena Procopio, Giovanni Ceccarini, Ferruccio Santini
    International Journal of Molecular Sciences.2025; 26(19): 9751.     CrossRef
  • Rare digestive disease: Mitochondrial neurogastrointestinal encephalomyopathy, review of the literature
    Ying Hao Sun, Xiao Yin Bai, Tao Guo, Si Yuan Fan, Ge Chong Ruan, Wei Xun Zhou, Hong Yang
    Journal of Digestive Diseases.2024; 25(9-10): 624.     CrossRef
  • Intensive nutrition support may benefit patients with a rare mitochondrial disorder
    Arezina Kasti, Maroulla Nikolaki, Ioannis Pyrousis, Kalliopi Synodinou, Nikolaos Oikonomopoulos, Konstantinos Triantafyllou
    Nutrition in Clinical Practice.2022; 37(2): 361.     CrossRef
  • Serviceability Properties of Solid Buoyancy Materials for Deep-Sea HOV
    Hailong Zhang, Guoliang Ma, Zhiwei Zhu, Antonio Gloria
    Advances in Materials Science and Engineering.2022; 2022: 1.     CrossRef
  • Loss of thymidine phosphorylase activity disrupts adipocyte differentiation and induces insulin-resistant lipoatrophic diabetes
    Jérémie Gautheron, Lara Lima, Baris Akinci, Jamila Zammouri, Martine Auclair, Sema Kalkan Ucar, Samim Ozen, Canan Altay, Bridget E. Bax, Ivan Nemazanyy, Véronique Lenoir, Carina Prip-Buus, Cécile Acquaviva-Bourdain, Olivier Lascols, Bruno Fève, Corinne Vi
    BMC Medicine.2022;[Epub]     CrossRef
  • Case report: A patient with mitochondrial neurogastrointestinal encephalomyopathy and chronic intestinal failure
    Ana Barisic, Dina Ljubas Kelecic, Darija Vranesic Bender, Irena Karas, Marko Brinar, Vladimir Miletic, Zeljko Krznaric
    Frontiers in Nutrition.2022;[Epub]     CrossRef
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    Jason Duran, Armando Martinez, Eric Adler
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  • Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy
    Michelle Levene, Murray D. Bain, Nicholas F. Moran, Niranjanan Nirmalananthan, Joanna Poulton, Mauro Scarpelli, Massimiliano Filosto, Hanna Mandel, Andrew D. MacKinnon, Lynette Fairbanks, Dario Pacitti, Bridget E Bax
    Journal of Clinical Medicine.2019; 8(4): 457.     CrossRef
  • Mitochondrial Neurogastrointestinal Encephalomyopathy: Into the Fourth Decade, What We Have Learned So Far
    Dario Pacitti, Michelle Levene, Caterina Garone, Niranjanan Nirmalananthan, Bridget E. Bax
    Frontiers in Genetics.2018;[Epub]     CrossRef
  • Cerebral Manifestations of Mitochondrial Disorders
    Josef Finsterer, Elmano Henrique Torres de Carvalho
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.2017; 44(6): 654.     CrossRef
  • Mitochondrial Neurogastrointestinal Encephalomyopathy Caused by Thymidine Phosphorylase Enzyme Deficiency: From Pathogenesis to Emerging Therapeutic Options
    Rana Yadak, Peter Sillevis Smitt, Marike W. van Gisbergen, Niek P. van Til, Irenaeus F. M. de Coo
    Frontiers in Cellular Neuroscience.2017;[Epub]     CrossRef
  • Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis
    Anastasia Asimakopoulou, Annabelle Fülöp, Erawan Borkham-Kamphorst, Eddy Van de Leur, Nikolaus Gassler, Thorsten Berger, Birte Beine, Helmut E. Meyer, Tak W. Mak, Carsten Hopf, Corinna Henkel, Ralf Weiskirchen
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.2017; 1863(9): 2093.     CrossRef
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[English]

Chronic obstructive pulmonary disease (COPD) is a major cause of disability, and according to statistics from the World Health Organization, COPD is the fourth leading cause of death overall in the face of decades, and expected to be increased. In 2005, the reported prevalence of COPD in Korea was 17.2% of adults over the age of 45. Malnutrition is a common problem in papatients with COPD. And several nutritional intervention studies showed a significant improvement in physical and functional outcomes. According to the results of previous studies, the nutritional support is important. This is a case report of a patient with COPD who was introduced to a proper diet through nutrition education based on the medical nutrition therapy protocol for COPD.

Citations

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  • Effect of Macronutrients or Micronutrients Supplementation on Nutritional Status, Physical Functional Capacity and Quality of Life in Patients with COPD: A Systematic Review and Meta-Analysis
    Greta Lattanzi, Diana Lelli, Raffaele Antonelli Incalzi, Claudio Pedone
    Journal of the American Nutrition Association.2024; 43(5): 473.     CrossRef
  • Kronik Obstrüktif Akciğer Hastalığı Olan Malnütrisyonlu Bireylerde Hemşirelik Yaklaşımı
    Gizem ÖZBUDAK, Öznur USTA YEŞİLBALKAN, Asiye AKYOL
    Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi.2022; 15(3): 387.     CrossRef
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Original Articles
[English]
Effect of the Telephone-Delivered Nutrition Education on Dietary Intake and Biochemical Parameters in Subjects with Metabolic Syndrome
Juyoung Kim, Wookyung Bea, Kiheon Lee, Jongsoo Han, Sohye Kim, Misung Kim, Woori Na, Cheongmin Sohn
Clin Nutr Res 2013;2(2):115-124.   Published online July 23, 2013
DOI: https://doi.org/10.7762/cnr.2013.2.2.115

As prevalence of metabolic syndrome has rapidly increased over the past decade, lifestyle changes including dietary habits are considered as a therapeutic cornerstone for metabolic syndrome, cardiovascular complications and type 2 diabetes. We evaluated the effectiveness of a telephone-delivered nutrition education to improve metabolic parameters compared with a single-visit with a dietitian in subjects with metabolic syndrome. A total of seventy-one adults who met diagnostic criteria for the metabolic syndrome were randomly assigned to either the single-visit group or the in-depth nutrition education group during a 3-month intervention study period. The in-depth telephone-delivered nutrition education group had an initial visit with a dietitian and additional two telephone counseling during the first 4 weeks of the study periods. Sixty-six subjects completed a 3-month intervention study. The trial examined participant's anthropometric changes and dietary intakes as well as changes in the metabolic syndrome factors. At the end of the trial, the in-depth nutrition education group showed significantly higher reduction in weight, body fat and abdominal circumference compared with the other group (p < 0.05). In the in-depth nutrition groups, the prevalence of metabolic syndrome was decreased to 45.5%, while 69.7% of the subjects were metabolic syndrome patients in the single-visit group (p < 0.05). These results demonstrate that the telephone-intervention counseling is a feasible mean to deliver dietary intervention in patients with metabolic syndrome.

Citations

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  • Effects of nutrition education, physical activity and motivational interviewing interventions on metabolic syndrome among females of reproductive age in Wakiso district, central Uganda: a randomised parallel-group trial
    David Lubogo, Henry Wamani, Roy William Mayega, Christopher Garimoi Orach
    BMC Public Health.2025;[Epub]     CrossRef
  • The Feasibility and Effectiveness of Telenutrition for Remote Dietary Consultation: A Systematic Review and Meta-analysis
    Nur Liyana Hasnaa Mohd Daud, Noraishah Mohamed Nor, Nurul Hazirah Jaafar, Wan Azdie Mohd Abu Bakar, Nor Azwani Mohd Shukri
    Current Research in Nutrition and Food Science Journal.2025; 13(1): 46.     CrossRef
  • Effect of therapeutic lifestyle change on metabolic syndrome in adults: a randomized controlled trial
    Gebremedhin Gebreegziabiher, Tefera Belachew, Dessalegn Tamiru
    Scientific Reports.2025;[Epub]     CrossRef
  • Evaluation of Irisin Levels in Cancer Anorexia Cachexia Syndrome and the Relationship between Nutrition Education and Quality of Life
    Diler Us Altay, Duygu Mataracı Değirmenci, Salih Can Çelik, Abdullah Üner, Tevfik Noyan, Çağrı Akalın
    Cumhuriyet Science Journal.2024; 45(4): 636.     CrossRef
  • Prevalence of Metabolic Syndrome Based on Activity Type and Dietary Habits in Extremely Low-Income Individuals
    Kunxia Su, Yonghwan Kim, Yoonjung Park
    Nutrients.2024; 16(11): 1677.     CrossRef
  • Health Provider’s Feedback on Physical Activity Surveillance Using Wearable Device-Smartphone Application for Adults with Metabolic Syndrome; a 12-Week Randomized Control Study
    Minwoo Jang, Jong-Hwan Park, Gwon-Min Kim, Seunghwan Song, Up Huh, Du-ri Kim, Minji Sung, Young Jin Tak
    Diabetes, Metabolic Syndrome and Obesity.2023; Volume 16: 1357.     CrossRef
  • Individual Diet Modification Reduces the Metabolic Syndrome in Patients Before Pharmacological Treatment
    Małgorzata Elżbieta Zujko, Marta Rożniata, Kinga Zujko
    Nutrients.2021; 13(6): 2102.     CrossRef
  • Competency-Based Training for Entrustment in Telehealth Consultations
    Elaine Lum, Louise Sandra van Galen, Josip Car
    Pediatric Clinics of North America.2020; 67(4): 735.     CrossRef
  • Personalized Nutrition Using PROCARDIO to Reduce Cardiometabolic Risk in the Academic Community: A Study Protocol with Preliminary Results
    Alinne Paula de Almeida, Daniela Mayumi Usuda Prado Rocha, Ana Vládia Bandeira Moreira, Hatanne Carla Fialho Moraes e Lima, Helen Hermana Miranda Hermsdorff
    Journal of the American College of Nutrition.2020; 39(7): 591.     CrossRef
  • Effect of electronic health interventions on metabolic syndrome: a systematic review and meta-analysis
    Dandan Chen, Zhihong Ye, Jing Shao, Leiwen Tang, Hui Zhang, Xiyi Wang, Ruolin Qiu, Qi Zhang
    BMJ Open.2020; 10(10): e036927.     CrossRef
  • Process evaluation of the ‘Singapore Physical Activity and Nutrition Study’
    Elaine Yee-Sing Wong, Andy H. Lee, Anthony P. James, Jonine Jancey
    Evaluation and Program Planning.2020; 83: 101847.     CrossRef
  • Prevention of Metabolic Syndrome by Telephone-Delivered Lifestyle Intervention in a Real-World Setting: Sub-Analysis of a Cluster-Randomized Trial
    Naoki Sakane, Kazuhiko Kotani, Akiko Suganuma, Kaoru Takahashi, Juichi Sato, Sadao Suzuki, Kazuo Izumi, Masayuki Kato, Mitsuhiko Noda, Shinsuke Nirengi, Hideshi Kuzuya
    Metabolic Syndrome and Related Disorders.2019; 17(7): 355.     CrossRef
  • Importance of Adherence to Personalized Diet Intervention in Obesity Related Metabolic Improvement in Overweight and Obese Korean Adults
    Juhyun An, So Ra Yoon, Jae Hayng Lee, Hyunyoung Kim, Oh Yoen Kim
    Clinical Nutrition Research.2019; 8(3): 171.     CrossRef
  • A retrospective analysis of the impact of telephonic counseling on dietary and lifestyle modifications in Indian patients with type 2 diabetes mellitus
    Viraj Salgaonkar, Amit Singh, Vikram Singh, Saimala Guntur
    International Journal of Diabetes in Developing Countries.2018; 38(4): 486.     CrossRef
  • Diet, Sleep and Metabolic Syndrome Among a Legal Amazon Population, Brazil
    Poliana Rodrigues dos Santos, Graziele Souza Lira Ferrari, Carlos K B Ferrari
    Clinical Nutrition Research.2015; 4(1): 41.     CrossRef
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[English]
Evaluation of Nutrient Intake in Early Post Kidney Transplant Recipients
Mi Ra Rho, Jeong Hyun Lim, Jung Hwa Park, Seung Seok Han, Yon Su Kim, Young Hee Lee, Won Gyoung Kim
Clin Nutr Res 2013;2(1):1-11.   Published online January 29, 2013
DOI: https://doi.org/10.7762/cnr.2013.2.1.1

The purpose of our study was to evaluate the dietary intake of kidney transplant recipients (KTRs) and assess oral intake related nutrition problems. Fifty patients who had undergone kidney transplantation were included: 24 males, 26 females. The mean age was 46.8 ± 11.2 years, height was 161.3 ± 8.3 cm, and body weight was 60.5 ± 8.7 kg. We conducted nutrition education based on the diet guideline for KTRs (energy 32 kcal/kg of ideal body weight [IBW], protein 1.3 g/kg of IBW) and neutropenic diet guideline before discharge. Dietary intake of the patients at 1 month after transplantation was investigated by 3-day food records. Body weight and laboratory values for nutritional status and graft function were also collected. Body weight was significantly decreased from admission to discharge. Body weight from discharge to 1 month and 3 months after transplantation was increased but was not significant. Biochemical measurements were generally improved but the number of patients with hypophosphatemia increased. The daily dietary intake of energy and protein was adequate (33.1 kcal/kg, 1.5 g/kg, respectively). However, the dietary intake of calcium, folate, and vitamin C did not meet the Korean Recommended Nutrient Intake of vitamins and minerals (86.8%, 62.4%, and 88.0%, respectively). Patients with low intake of calcium, folate, and vitamin C presented low intake in milk and dairy products, vegetables, and fruits, and these foods were related to restricted food items in neutropenic diet. More attention should be paid on improving quality of diet, and reconsideration of present neutropenic diet guideline is necessary. These results can be used to establish evidence-based medical nutrition therapy guideline for KTRs.

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    Suzanne Schneider, Deborah Biggerstaff, Thomas M. Barber
    Transplant International.2025;[Epub]     CrossRef
  • Vitamin C deficiency after kidney transplantation: a cohort and cross-sectional study of the TransplantLines biobank
    Manuela Yepes-Calderón, Yvonne van der Veen, Fernando Martín del Campo S, Daan Kremer, Camilo G. Sotomayor, Tim J. Knobbe, Michel J. Vos, Eva Corpeleijn, Martin H. de Borst, Stephan J. L. Bakker
    European Journal of Nutrition.2024; 63(6): 2357.     CrossRef
  • Assessing nutrition status, sarcopenia, and frailty in adult transplant recipients
    Astrid Ruiz‐Margáin, Ricardo U. Macías‐Rodríguez, Nayelli C. Flores‐García, Berenice M. Román Calleja, Oscar M. Fierro‐Angulo, José A. González‐Regueiro
    Nutrition in Clinical Practice.2024; 39(1): 14.     CrossRef
  • Metabolic Syndrome and Dietary Intake are Associated With Quality of Life in Kidney Transplant Recipients
    Thu-Ha Nguyen, Zulfitri Azuan Mat Daud, Ruzita Abd. Talib, Rozita Mohd, Bee-Koon Poh
    Transplantation Proceedings.2023; 55(9): 2176.     CrossRef
  • Approccio nutrizionale all’ipofosforemia post-trapianto di rene: uno studio pilota
    Alessandra Zattarin, Francesco Francini-Pesenti, Claudia Da Col, Paolo Spinella, Marianna Alessi, Lucia Federica Stefanelli, Lorenzo A. Calò
    Giornale di Clinica Nefrologica e Dialisi.2022; 34: 74.     CrossRef
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    Francesca Gori, Jacopo Fumagalli, Caterina Lonati, Riccardo Caccialanza, Alberto Zanella, Giacomo Grasselli
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    I-Hsin Lin, Tuyen Van Duong, Te-Chih Wong, Shih-Wei Nien, I-Hsin Tseng, Yang-Jen Chiang, Hsu-Han Wang, Shwu-Huey Yang
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    I-Hsin Lin, Tuyen Van Duong, Shih-Wei Nien, I-Hsin Tseng, Hsu-Han Wang, Yang-Jen Chiang, Chia-Yen Chen, Te-Chih Wong
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    M. Jankowska, N. Szupryczyńska, A. Dębska-Ślizień, P. Borek, M. Kaczkan, B. Rutkowski, S. Małgorzewicz
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    Kyeong Woo Nho, Young Hoon Kim, Duck Jong Han, Su-Kil Park, Soon Bae Kim
    Transplantation.2015; 99(1): 133.     CrossRef
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