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"Basal metabolism"

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"Basal metabolism"

Original Article


Objective

Failure to achieve adequate caloric intake is common after percutaneous endoscopic gastrostomy (PEG) and may contribute to progressive malnutrition in older adults. This study aimed to identify factors associated with achieving adequate caloric delivery early after PEG placement.
Methods
This single-center retrospective observational study included patients aged ≥65 years who underwent PEG between January 2022 and December 2024. Target caloric intake was determined based on basal energy expenditure (BEE). The target nutritional intake achievement rate (TaNIAR) was defined as the ratio of final delivered calories to BEE. Patients were classified into an underfeeding group (TaNIAR <100%) and an appropriate-feeding group (TaNIAR ≥100%). Multivariable logistic regression analysis was performed to identify factors independently associated with achieving TaNIAR ≥100%.
Results
Fifty-nine patients were analyzed; 15 were classified as underfeeding and 44 as appropriate-feeding. The median final caloric intake, calculated in increments of 300 kcal corresponding to the packet size of the enteral formula, was 1,200 kcal (range, 600–1,200 kcal) in the underfeeding group and 1,200 kcal (range, 900–1,400 kcal) in the appropriate-feeding group. Multivariable analysis identified the use of a pectin-containing oligomeric formula (POF) (odds ratio [OR], 32.8; 95% confidence interval [CI], 3.7–292.9) and BEE ≤990 kcal/day (OR, 29.5; 95% CI, 3.1–277.7) as factors independently associated with achieving TaNIAR ≥100%. The final caloric intake clustered within a relatively narrow range in both groups.
Conclusion
Lower BEE and the use of POF were independently associated with achieving adequate caloric delivery after PEG placement. Optimization of enteral formula selection may represent a practical strategy to improve early nutritional adequacy in older patients. Further prospective studies are required to validate these findings.
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Case Report
Changes in Dietary Intake, Body Weight, Nutritional Status, and Metabolic Rate in a Pancreatic Cancer Patient
So Young Kim, Gyung Ah Wie, Woo Jin Lee, Sang-Jae Park, Sang Myung Woo
Clin Nutr Res 2013;2(2):154-158.   Published online July 23, 2013
DOI: https://doi.org/10.7762/cnr.2013.2.2.154

Pancreatic cancer patients often have a poor prognosis and suffer from nutritional problems. Malnutrition is characterized by weight loss and decreased dietary intake, and is common among pancreatic cancer patients. The
objective
of this report was to describe the changes in dietary intake, body weight, nutritional status, and metabolic rate on a continuum from the time of diagnosis until the end of life in a patient with pancreatic cancer. In summary, the patient's nutritional status gradually declined, accompanied by extreme weight loss and decreased dietary intake. Conversely, resting energy expenditure, measured by indirect calorimetry, increased from 24 kcal/kg/day to 35 kcal/kg/day. Nutritional management during cancer treatment is important but may be challenging in pancreatic cancer patients.

Citations

Citations to this article as recorded by  
  • Energy Expenditure in Upper Gastrointestinal Cancers: a Scoping Review
    Lauren Hanna, Judi Porter, Judy Bauer, Kay Nguo
    Advances in Nutrition.2023; 14(6): 1307.     CrossRef
  • Assessment of nutritional status and quality of life in patients with pancreatic head cancer
    Imane Boussenna, Mohamed Acharki, Zineb Hannoun, Ikram Kenfaoui, Abdellatif Bour, S. Bourekkadi, H. Hami, A. Mokhtari, K. Slimani, A. Soulaymani
    E3S Web of Conferences.2021; 319: 02022.     CrossRef
  • Pankreaskarzinom − Bedeutung der Ernährung
    Christine Reudelsterz, Jutta Hübner, Nicole Tonya Erickson
    Der Onkologe.2019; 25(8): 717.     CrossRef
  • Effect of clinical status on survival in patients with borderline or locally advanced pancreatic adenocarcinoma
    Pauline Duconseil, Jonathan Garnier, Victoria Weets, Jacques Ewald, Ugo Marchese, Marine Gilabert, Laurence Moureau-Zabotto, Flora Poizat, Marc Giovannini, Jean-Robert Delpero, Olivier Turrini
    World Journal of Surgical Oncology.2019;[Epub]     CrossRef
  • Assessment of Nutritional Status, Digestion and Absorption, and Quality of Life in Patients with Locally Advanced Pancreatic Cancer
    J. E. Witvliet-van Nierop, C. M. Lochtenberg-Potjes, N. J. Wierdsma, H. J. Scheffer, G. Kazemier, K. Ottens-Oussoren, M. R. Meijerink, M. A. E. de van der Schueren
    Gastroenterology Research and Practice.2017; 2017: 1.     CrossRef
  • Outcomes of Systematic Nutritional Assessment and Medical Nutrition Therapy in Pancreatic Cancer
    Pankaj Vashi, Brenten Popiel, Carolyn Lammersfeld, Digant Gupta
    Pancreas.2015; 44(5): 750.     CrossRef
  • Anorexia–cachexia syndrome in pancreatic cancer: Recent advances and new pharmacological approach
    Ilaria Ronga, Fernando Gallucci, Ferdinando Riccardi, Generoso Uomo
    Advances in Medical Sciences.2014; 59(1): 1.     CrossRef
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  • 7 Crossref