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Review Article

Vitamin D and The Gut Microbiota: a Narrative Literature Review

Hadith Tangestani1orcid, Hossein Khosravi Boroujeni2orcid, Kurosh Djafarian3orcid, Hadi Emamat4orcid, Sakineh Shab-Bidar5orcid
Clinical Nutrition Research 2021;10(3):181-191.
Published online: July 20, 2021

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Correspondence to Sakineh Shab-Bidar. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), No 44, Hojjat-dost Alley, Naderi St., Keshavarz Blvd, Tehran 14155-6117, Iran. s_shabbidar@tums.ac.ir
• Received: August 16, 2020   • Revised: June 3, 2021   • Accepted: June 21, 2021

Copyright © 2021. The Korean Society of Clinical Nutrition

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Vitamin D and The Gut Microbiota: a Narrative Literature Review
Clin Nutr Res. 2021;10(3):181-191.   Published online July 20, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.3.181
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Vitamin D and The Gut Microbiota: a Narrative Literature Review
Clin Nutr Res. 2021;10(3):181-191.   Published online July 20, 2021
DOI: https://doi.org/10.7762/cnr.2021.10.3.181
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Vitamin D and The Gut Microbiota: a Narrative Literature Review
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Figure 1 Suggested mechanisms for the association of vitamin D and microbiota.RXR, retinoid X receptor; VDR, vitamin D receptor; VDRE, vitamin D response element; ZO, zonula occludens; TLR, Toll-like receptor; NOD, nucleotide oligomerization domain; NF-κB, nuclear factor kappa B; LPS, lipopolysaccharides.

Figure 1

Vitamin D and The Gut Microbiota: a Narrative Literature Review
Table 1 Summary of animal studies

qRT-PCR, quantitative real time polymerase chain reaction; qPCR, quantitative polymerase chain reaction; VDR, vitamin D receptor; PND, postnatal days; LPS, lipopolysaccharides; KO, knockout; Cyp, cytochrome P; rRNA, ribosomal ribonucleic acid; NR, not reported.

Table 2 Summary of interventional and observational human studies

PCR, polymerase chain reaction; rRNA, ribosomal ribonucleic acid; NR, not reported; RT-PCR, reverse transcription polymerase chain reaction.

Table 1

Table 2

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