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"Formulated food"

Review Article
Food for Special Medical Purposes: A Global Review of Usage Trends, Regulatory Frameworks, and Key Growth Drivers
Hae Jin Kang, Yoo Kyoung Park
Clin Nutr Res 2025;14(2):146-156.   Published online April 28, 2025
DOI: https://doi.org/10.7762/cnr.2025.14.2.146

This review offers a comprehensive analysis of food for special medical purposes (FSMPs)—specially formulated foods designed to support the dietary management of individuals with specific medical conditions. The regulatory frameworks governing FSMP differ significantly across key regions, including the European Union, North America (with a focus on the United States), and Asia (primarily China and India). FSMP is critical in addressing malnutrition, metabolic disorders (including inborn errors of metabolism), and chronic diseases, such as cancer, diabetes, and neurological conditions. Recent advancements, such as the application of three-dimensional printing technology and the growing emphasis on personalized nutrition, are poised to revolutionize the FSMP industry. The global market for FSMP is experiencing rapid growth, particularly in China, driven by factors like aging populations and the increasing prevalence of chronic diseases. Future trends suggest a shift toward more personalized, technologically advanced FSMP formulations. However, challenges such as high costs, limited accessibility, unclear regulations, and poor palatability must be addressed to maximize the potential of FSMP in enhancing patient care.

Citations

Citations to this article as recorded by  
  • Foods for special medical purposes for the dietary therapy of rare diseases: Current status and future prospects
    Ting Zhang, Yun Wang, Cuiping Shi, Ye Zi, Wei Cai, Jian Zhong
    Intractable & Rare Diseases Research.2026; 15(1): 26.     CrossRef
  • Clinical field survey and multidisciplinary expert in-depth interview study on food for special medical purpose products for patients
    Ju Hee Kang, Hee-Jung Park, Hyo Jeong Lim, Jung Joo Lee, Bo-Eun Kim, Eun Joo Bae, Yeon Hee Lee, Dal Lae Ju, Young Ran Kim, Jin-Hee Yeom, Hee-Sook Lim, Ha-Neul Kim, Seul Bi Lee, Seo-Yeon Park, Hee Joon Baek, Yoo Kyoung Park
    Clinical Nutrition Research.2026; 15(1): 12.     CrossRef
  • Food as Medicine: Integrating Food-Medicine Homology into Foods for Special Medical Purposes for Targeted Symptom Management and Nutritional Support
    Zhengyang Liu, Shengqian Sun, Yue Zhang, Hefei Zhao, Changmou Xu, Yongjun Liu, Huilian Che
    Food Reviews International.2026; : 1.     CrossRef
  • Sensory Acceptability and Sensory Profiles of Flavoured Foods for Special Medical Purposes: A Quantitative Descriptive Analysis
    Agata Kiciak, Wiktoria Staśkiewicz-Bartecka, Natalia Kuczka, Małgorzata Słoma-Krześlak, Kommi Kalpana, Marek Kardas
    Journal of Clinical Medicine.2026; 15(6): 2188.     CrossRef
  • Clinical application and institutional governance of foods for special medical purposes in medical institutions of eastern coastal China: a cross-sectional study
    Qingqing Deng, Wanli Pu, Ting Zhu, Jiayao Yang, Junxuan Chen, Xiaosu Chen, Qing Zhao, Yue Xu, Shu-an Wang, Fangjun Chen, Xiaotian Chen
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Food-derived bioactive compounds targeting mitophagy: Emerging nutritional strategies against sarcopenia
    Haozhen Zhang, Laiming Zhang, Donghong Liu, Xingqian Ye, Shiguo Chen
    Trends in Food Science & Technology.2025; 165: 105314.     CrossRef
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