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"Dietary supplements"

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"Dietary supplements"

Original Articles
[English]
Effects of Replacing Skipped Meals With Oral Nutritional Supplement on Nutritional Status and Physical Function in Older Adults
Jiyeon Lee, Seong Ah Cho, Seoyoon Choi, Eunbi Han, Hyeri Shin, Yoo Kyoung Park
Clin Nutr Res 2025;14(3):191-203.   Published online July 29, 2025
DOI: https://doi.org/10.7762/cnr.2025.14.3.191

This study evaluated the effects of replacing skipped meals with oral nutritional supplements (ONS) on the nutritional status and functional health of older adults. A total of 29 participants aged ≥ 65 years who regularly skipped at least one meal per day were included in this single-arm study. For 8 weeks, participants consumed two packs of ONS daily (150 mL each, providing 400 kcal and 18 g of protein) as a substitute for skipped meals. Nutritional status, nutrient intake, body composition, and physical function were assessed before and after the intervention. The Nutrition Quotient for the Elderly score significantly increased from 58.97 to 63.62 (p = 0.014). Total nutrient intake, including ONS, significantly improved compared with baseline (p < 0.01). Body weight and body mass index increased significantly from 58.87 to 59.47 kg (p = 0.028) and from 23.9 to 24.18 kg/m2 (p = 0.016), respectively. Calf circumference decreased significantly from 34.1 to 33.39 cm (p = 0.010). Physical function, assessed using the Short Physical Performance Battery, showed significant improvement (p = 0.003). In conclusion, replacing skipped meals with ONS may enhance nutritional status and support functional health in older adults.

Trial Registration

Clinical Research Information Service Identifier: KCT0010184

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[English]
Evaluation of Mineral Contents of Multi-Vitamin and Minerals Currently Sold in South Korea
Mi-Kyeong Choi, Eun-Sun Park, Mi-Hyun Kim
Clin Nutr Res 2018;7(4):248-255.   Published online October 30, 2018
DOI: https://doi.org/10.7762/cnr.2018.7.4.248

Dietary supplements are popular worldwide and their use has been increasing. The purpose of this study was to evaluate the mineral contents of multi-vitamins and minerals (MVMs) in most commonly sold among dietary supplements. Ninety popular MVM supplements sold in South Korea were surveyed regarding their characteristics and ingredients including minerals listed on the labels through off-line and on-line search. Daily mineral contents of the MVM supplements were compared with Korean Dietary Reference Intakes (DRIs) by target populations. The average price of 90 MVM supplements was $41.3 per bottle, with a price of $0.9 per day and the average number of minerals contained per supplement was 4.7. A total 14 minerals were found in the MVM supplements including calcium, phosphorus, sodium, potassium, and magnesium. Nine minerals (e.g. calcium, magnesium, and iron) were included in more than 30% of the MVM supplements examined. When daily mineral dose of MVMs was compared to DRIs, calcium was the lowest (34.0% of recommended intake [RI]) and chromium was the highest (218.7% of adequate intake [AI]), and zinc, copper, selenium, and chromium were also higher than their RI or AI levels. The daily mineral contents of the 90 MVM supplements were below the tolerable upper-intake level, but some minerals were higher than RI or AI with high variance among products. Therefore, there is a great need to educate the public for the adequate selection and use of MVM supplements based on the contents of MVM supplements and individual's mineral intake derived from the diet.

Citations

Citations to this article as recorded by  
  • Monitoring of Essential and Toxic Elements in Multivitamin/Mineral Effervescent Tablet Supplements and Safety Assessment
    İrem Uslu, Orkun Alp, Bensu Karahalil
    Biological Trace Element Research.2025; 203(1): 499.     CrossRef
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[English]
Intakes of Iron and Folate and Hematologic Indices According to the Type of Supplements in Pregnant Women
Eunah Park, Hee-Chul Lee, Jung-Youl Han, June-Seek Choi, Taisun Hyun, Youngshin Han
Clin Nutr Res 2012;1(1):78-84.   Published online July 26, 2012
DOI: https://doi.org/10.7762/cnr.2012.1.1.78

Adequate amounts of nutrients during pregnancy are essential for maternal, fetal and child health. This study was conducted to investigate the intakes of iron and folate and the effect of supplements on anemia status during pregnancy. One hundred sixty five pregnant women completed questionnaires which included food frequencies and supplement use, and blood tests for hematologic indices. Pregnant women were divided into four groups based on the type of supplements; single nutrient group (S), multivitamins & minerals group (M), Single nutrient + multivitamins & minerals group (S+M), and no supplement group (N). Mean iron intake was 11.1 mg from food (46.3% of Recommended Nutrient Intakes, RNIs) and 66.8 mg from supplements. Mean folate intake was 231.2 µg from food (38.5% of RNI) and 822.7 µg from supplements. In the N group, the subjects who consumed iron and folate less than EAR were 85.7% and 95.2%, respectively. The subjects consumed iron more than UL were 81.0% in the S group, 88.9% in the M group, and 97.4% in the S+M group, and the subjects consumed folate more than UL were 4.8% in the S group, 1.6% in the M group, and 25.6% in the S+M group. The mean values of hemoglobin and hemotocrit in the M group were significantly higher than those in the N group. Despite the relatively high socio-economic status of the participants, overall intakes of iron and folate from food were far below the RNIs, suggesting that a supplement is needed for adequate nutritional status during pregnancy. A multivitamin supplement seems to be more effective than a single nutrient supplement such as iron or folic acid in the prevention of anemia. Further research is required to define the appropriate amount of supplemental iron and folic acid for Korean pregnant women.

Citations

Citations to this article as recorded by  
  • Nutritional status and dietary diversity of pregnant and nonpregnant reproductive‐age Rohingya women
    Shah Mohammad Fahim, Subhasish Das, Md. Golam Rasul, Mahabub Uz Zaman, Md. Ashraful Alam, Sazia Afrin, Kazi Nazmus Saqeeb, Md. Mahmudul Hasan, A. F. M. Mahbubul Alam, Morseda Chowdhury, Tahmeed Ahmed
    Food Science & Nutrition.2023; 11(9): 5523.     CrossRef
  • Folate: 2020 Dietary reference intakes and nutritional status of Koreans
    Young-Hee Han, Taisun Hyun
    Journal of Nutrition and Health.2022; 55(3): 330.     CrossRef
  • Higher maternal vitamin D concentrations are associated with longer leukocyte telomeres in newborns
    Jung‐Ha Kim, Gwang Jun Kim, Donghee Lee, Jae‐Hong Ko, Inja Lim, Hyoweon Bang, Bart W. Koes, Byeongchan Seong, Duk‐Chul Lee
    Maternal & Child Nutrition.2018;[Epub]     CrossRef
  • Nutrient Composition and Content of Vitamin and Mineral Supplements and Their Appropriateness for Pregnant and Lactating Women in Korea
    Young-Hee Han, Jeong-Hyeon Seo, Gu-Rum Shin, Ju-Young Shin, Ye-Young Jo, Taisun Hyun
    Korean Journal of Community Nutrition.2018; 23(4): 341.     CrossRef
  • Preconceptional use of folic acid and knowledge about folic acid among low-income pregnant women in Korea
    Jihyun Kim, Miyong Yon, Cho-il Kim, Yoonna Lee, Gui-Im Moon, Jinhwan Hong, Taisun Hyun
    Nutrition Research and Practice.2017; 11(3): 240.     CrossRef
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