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"Bora Lee"

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"Bora Lee"

Original Articles
[English]
Association between Inflammatory Biomarkers and Nutritional Status in Fatty Liver
Hee-Sook Lim, Joungyun Choi, Bora Lee, Sang Gyune Kim, Young Seok Kim, Jeong-Ju Yoo
Clin Nutr Res 2020;9(3):182-194.   Published online July 28, 2020
DOI: https://doi.org/10.7762/cnr.2020.9.3.182

The prevalence and progression of non-alcoholic fatty liver disease (NAFLD) is mediated via several factors correlating with hepatic necroinflammation (adipokines/cytokines). This study was performed to analyze the level of inflammatory markers according to the presence of NAFLD and to identify related nutritional factors. A total of 80 adults were classified into 2 groups (healthy and NAFLD), and their body composition, blood tests, and eating habits were evaluated. In addition, inflammatory markers (adiponectin, high-sensitivity C-reactive protein [CRP], and tumor necrosis factor-alpha [TNF-α]), nutrient intake status, and dietary quality were compared. The quality of diet was assessed according to the nutrient adequacy ratio and the mean adequacy ratio (MAR). The NAFLD group had a higher body mass index (p < 0.001) than the healthy group and also carried significantly higher CRP levels (p < 0.001) but lower adiponectin (p = 0.001). TNF-α levels increased significantly with fatty liver grade (p = 0.023). The NAFLD group showed significantly higher intake of energy, carbohydrates, iron, sodium, vitamin A and saturated fatty acids, but significantly lower intake of zinc and vitamin E than the healthy group. The MAR values were slightly higher in the NAFLD group but without any significant difference. The levels of adiponectin and vitamin E showed a significant inverse correlation (p < 0.05). Nutritional management of NAFLD patients is important, and the intake of antioxidant and anti-inflammatory nutrients such as zinc and vitamin E should be emphasized.

Citations

Citations to this article as recorded by  
  • Plant-Based Retinol Intake and Risk of Nonalcoholic Fatty Liver Disease in American Adults: Insights from NHANES 2007-2014
    Can Liu, Zeming Bai, Jingmin Cheng
    World Journal of Public Health.2025; 10(3): 379.     CrossRef
  • Recent Progresses on Pathophysiology, Diagnosis, Therapeutic Modalities, and Management of Non-alcoholic Fatty Liver Disorder
    Mahdi Barazesh, Sajad Jalili, Morteza Akhzari, Fouzieyeh Faraji, Ebrahim Khorramdin
    Current Drug Therapy.2024; 19(1): 20.     CrossRef
  • Association between dietary vitamin A intake from different sources and non-alcoholic fatty liver disease among adults
    Can Liu, Xiaona Sun, Jing Peng, Haiqing Yu, Jiao Lu, Yihui Feng
    Scientific Reports.2024;[Epub]     CrossRef
  • Synergistic impact of Composite Dietary Antioxidant Index and physical activity on fatty liver disease
    Linxiao Gao, Haoyu Fang, Zhibo Zhao, Wen Luo, Jianping Gong, Junhua Gong
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • High-Sensitivity C-Reactive Protein Levels in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Metabolic Alcohol-Associated Liver Disease (MetALD), and Alcoholic Liver Disease (ALD) with Metabolic Dysfunction
    Seong-Uk Baek, Jin-Ha Yoon
    Biomolecules.2024; 14(11): 1468.     CrossRef
  • The association between serum vitamin A and NAFLD among US adults varied in different BMI groups: a cross-sectional study
    Kaiwen Zhang, Jiayida Nulali, Caoxu Zhang, Yingchao Chen, Jing Cheng, Xiaye Shi, Chunfang Zhu, Yingli Lu, Ningjian Wang, Bing Han
    Food & Function.2023; 14(2): 836.     CrossRef
  • Dietary Acid Load (DAL), Glycated Hemoglobin A1c (HbA1c), and Metabolic Syndrome (MeS) Mediate the Association of the Adherence to the Dietary Approaches to Stopping Hypertension (DASH) and Mediterranean Diet (MeD) With Nonalcoholic Fatty Liver Disease
    Azam Doustmohammadian, Sakineh Nouri Saeidlou, Saeed Esfandyari, Esmaeel Gholizadeh, Mansooreh Maadi, Nima Motamed, Hossein Ajdarkosh, Mahmoodreza Khoonsari, Cain C. T. Clark, Farhad Zamani
    Frontiers in Nutrition.2022;[Epub]     CrossRef
  • The Role of Vitamin Deficiency in Liver Disease: To Supplement or Not Supplement?
    Anna Licata, Maddalena Zerbo, Silvia Como, Marcella Cammilleri, Maurizio Soresi, Giuseppe Montalto, Lydia Giannitrapani
    Nutrients.2021; 13(11): 4014.     CrossRef
  • Roles of vitamin A in the regulation of fatty acid synthesis
    Fu-Chen Yang, Feng Xu, Tian-Nan Wang, Guo-Xun Chen
    World Journal of Clinical Cases.2021; 9(18): 4506.     CrossRef
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[English]
Short Term Intake of Undaria pinnatifida Does Not Affect Bone Biomarkers in Young Korean Women with Low Calcium Intake
Clara Yongjoo Park, Bora Lee, Sung Jae Lee
Clin Nutr Res 2020;9(2):90-96.   Published online April 22, 2020
DOI: https://doi.org/10.7762/cnr.2020.9.2.90

Calcium intake is essential for bone health, but young Korean women have low calcium intakes. Seaweeds have high calcium content, which may affect calcium metabolism. Twenty nine females aged 18–39 years with low calcium intake (< 400 mg/day) participated in a 19-day open-label randomized controlled trial. During the first five days, participants adhered to a controlled-feeding protocol followed by a two-week supplementation period in free-living conditions. The treatment group (n = 14) received an additional 200 mg Ca/day through Undaria pinnatifida and Porphyra in meals during the controlled-feeding period, and as U. pinnatifida noodles during days 6–19. Mineral intake (Ca, P, Mg, Na, and K) was assessed from diet composites and three 24-hour recalls during the controlled-feeding and free-living periods, respectively. Fasting serum levels of calcium, 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D (1,25[OH]D), phosphorus, parathyroid hormone (PTH), and alkaline phosphatase (ALP) were assessed at baseline, day 6, and day 19. Statistical analyses were performed by Student's t-test and mixed ANOVA. Mean intakes of all minerals during days 1–5 and mean Ca and Mg intakes during days 6–19 were greater in the treatment group compared to the control group. No group effect or group and time interaction was observed in serum biomarkers. Serum 1,25(OH)D increased while PTH and ALP tended to decrease on day 6 but returned to baseline values on day 20. Short-term intake of U. pinnatifida and Porphyra does not affect calcium metabolism in young Korean women with low calcium intakes.

Trial Registration

Clinical Research Information Service Identifier: KCT0003307

Citations

Citations to this article as recorded by  
  • Effects of whole seaweed consumption on humans: current evidence from randomized-controlled intervention trials, knowledge gaps, and limitations
    João P. Trigo, Marie Palmnäs-Bédard, Mar Vall-Llosera Juanola, Ingrid Undeland
    Frontiers in Nutrition.2023;[Epub]     CrossRef
  • A short education session increases the accuracy of estimated food records in young Korean women during a controlled-feeding study
    Seunghee Kim, Bora Lee, Clara Yongjoo Park
    Nutrition Research and Practice.2021; 15(5): 613.     CrossRef
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  • 2 Crossref
[English]
Marine Healing, but Not Additional Intake of Undaria pinnatifida, Benefits Physical and Emotional Exhaustion Symptoms of Menopause
Hyunju Yun, Bora Lee, Sung Jae Lee, Clara Yongjoo Park
Clin Nutr Res 2020;9(1):1-10.   Published online December 26, 2019
DOI: https://doi.org/10.7762/cnr.2020.9.1.1

Menopausal symptoms can persist or worsen even years after menopause and affect women's quality of life. We investigated whether menopausal symptoms were alleviated through a marine healing program and if sea mustard intake additionally benefits these symptoms. A total of 42 menopausal women self-selected to participate as the marine (n = 22) or city group (n = 20). The marine group participated in a 5-day marine healing program consisting of a balanced diet, exercise, and mind-body practices using ocean resources. The city group continued one's daily routine without any intervention. Within the marine group, participants were randomly assigned to consume sea mustard (Undaria pinnatifida) (15.4 g dry weight/day; n = 11) or control (n = 11). Changes in menopausal symptoms were measured using the Menopause Rating Scale (MRS) before, immediately after, and 2 weeks after the end of the marine healing program. The city group completed the MRS at baseline and on day 20. Within subject differences of menopausal symptoms between baseline and immediately after the marine healing program were assessed using paired t-test. Intervention effects were assessed by mixed analysis of variance. Somatic, psychological, and urogenital symptoms were immediately alleviated after the marine healing program. No effect of sea mustard was detected in the marine group. After 2 weeks, the effect of marine healing persisted in physical and mental exhaustion only. A 5-day integrated marine healing program, but not additional sea mustard intake, temporarily alleviated menopausal symptoms. The reduction in physical and mental exhaustion after marine healing can be maintained for 2 weeks.

Trial Registration

Clinical Research Information Service Identifier: KCT0004025

Citations

Citations to this article as recorded by  
  • The need for biopsychosocial menopause care: a narrative review
    Subhadra Evans, Leesa Van Niekerk, Liliana Orellana, Melissa O'Shea, Marilla I. Druitt, Sara Jones, Sarah Corrigan, Campbell Heggen, Zuleika Arashiro, Rodney Baber, Lata Satyen, Dave Skvarc, Antonina Mikocka-Walus
    Menopause.2024; 31(12): 1090.     CrossRef
  • Changes in cortisol awakening responses (CAR) in menopausal women through short-term marine healing retreat program with specific factors affecting each CAR index
    Yesol Moon, Eunil Lee, Seoeun Lee, Gwang-Ic Son, Hangjin Byeon, Hyang-Ree Shin, Baatar Bolortsetseg, Juan-Luis Castillo-Navarrete
    PLOS ONE.2023; 18(4): e0284627.     CrossRef
  • Validity of Interviewer-Administered 24-h Dietary Recalls in Older Korean Women: A Pilot Study
    Seunghee Kim, Clara Y. Park
    Nutrients.2023; 15(7): 1757.     CrossRef
  • The Health-Promoting Properties of Seaweeds: Clinical Evidence based on Wakame and Kombu
    Eric Wei Chiang Chan, Mio Kezuka, Hung Tuck Chan, Siu Kuin Wong
    Journal of Natural Remedies.2023; : 687.     CrossRef
  • 5 View
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  • 4 Crossref